Pourmand Technology

Pourmand research is motivated by the philosophy that the best way to accelerate discovery is to develop innovative tools that will enable sweeping advances in knowledge, and to demonstrate such advances through the application of newly developed technologies. The choice of new technologies to be developed is driven by questions that cannot be answered with existing tools; conversely, the new tools of interest to our team invariably enable additional questions to be asked. The UCSC Biotechnology group is an ideal home for developing and applying new technologies that require approaching biological problems from an engineering perspective, not common in traditional biological research. We are seizing many opportunities in Bioengineering and Biology to develop and apply new technologies to broaden the field and support other biomedical research.



A nanopipette is so small it can penetrate a single cell without causing serious damage

A nanopipette is so small it can penetrate a single cell without causing serious damage

Nanopipette technology wins first place in NIH 'Follow that Cell' challenge

Nader Pourmand, professor of biomolecular engineering in the Baskin School of Engineering at UC Santa Cruz, has won the $300,000 first place prize in the Follow that Cell Challenge organized by the National Institutes of Health (NIH).


Single-cell nanobiopsy reveals compartmentalization of mRNAs within neuronal cells

The ability to study the molecular biology of living single cells in heterogeneous cell populations is essential for next generation analysis of cellular circuitry and function. Here, we developed a single-cell nanobiopsy platform based on scanning ion conductance microscopy (SICM) for continuous sampling of intracellular content from individual cells.


New technique allows 'nanobiopsies' of living cells

Researchers at UC Santa Cruz have developed a robotic "nanobiopsy" system that can extract tiny samples from inside a living cell without killing it. The single-cell nanobiopsy technique is a powerful tool for scientists working to understand the dynamic processes that occur within living cells, according to Nader Pourmand, professor of biomolecular engineering in UCSC's Baskin School of Engineering.